Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Phox2b  paired-like homeobox 2b   (Synonyms: Dilp1, GENA 269, NBPhox, Phox2b, Pmx2b, Px2b)
Results	Reference
1*	J:130196 Alfonsi F, Filippi P, Salaun D, deLapeyriere O, Durbec P, LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78
1	J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627
1	J:138626 Callahan T, Young HM, Anderson RB, Enomoto H, Anderson CR, Development of satellite glia in mouse sympathetic ganglia: GDNF and GFRalpha1 are not essential. Glia. 2008 Oct;56(13):1428-37
1	J:179212 Chen Y, Moon AM, Gaufo GO, Influence of mesodermal Fgf8 on the differentiation of neural crest-derived postganglionic neurons. Dev Biol. 2012 Jan 1;361(1):125-36
1	J:224198 Chen Y, Takano-Maruyama M, Fritzsch B, Gaufo GO, Hoxb1 controls anteroposterior identity of vestibular projection neurons. PLoS One. 2012;7(4):e34762
1*	J:174215 Chen Y, Takano-Maruyama M, Gaufo GO, Plasticity of neural crest-placode interaction in the developing visceral nervous system. Dev Dyn. 2011 Aug;240(8):1880-8
1	J:157532 Coppola E, Rallu M, Richard J, Dufour S, Riethmacher D, Guillemot F, Goridis C, Brunet JF, Epibranchial ganglia orchestrate the development of the cranial neurogenic crest. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2066-71
1	J:160023 Cossais F, Sock E, Hornig J, Schreiner S, Kellerer S, Bosl MR, Russell S, Wegner M, Replacement of mouse Sox10 by the Drosophila ortholog Sox100B provides evidence for co-option of SoxE proteins into vertebrate-specific gene-regulatory networks through altered expression. Dev Biol. 2010 May 1;341(1):267-81
1*	J:86516 Dauger S, Pattyn A, Lofaso F, Gaultier C, Goridis C, Gallego J, Brunet JF, Phox2b controls the development of peripheral chemoreceptors and afferent visceral pathways. Development. 2003 Dec;130(26):6635-42
1	J:175535 Deng Q, Andersson E, Hedlund E, Alekseenko Z, Coppola E, Panman L, Millonig JH, Brunet JF, Ericson J, Perlmann T, Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development. Development. 2011 Aug;138(16):3399-408
1	J:211702 Dyachuk V, Furlan A, Shahidi MK, Giovenco M, Kaukua N, Konstantinidou C, Pachnis V, Memic F, Marklund U, Muller T, Birchmeier C, Fried K, Ernfors P, Adameyko I, Neurodevelopment. Parasympathetic neurons originate from nerve-associated peripheral glial progenitors. Science. 2014 Jul 4;345(6192):82-7
1	J:114185 Enomoto H, Heuckeroth RO, Golden JP, Johnson EM, Milbrandt J, Development of cranial parasympathetic ganglia requires sequential actions of GDNF and neurturin. Development. 2000 Nov;127(22):4877-89
1	J:196818 Espana A, Clotman F, Onecut factors control development of the Locus Coeruleus and of the mesencephalic trigeminal nucleus. Mol Cell Neurosci. 2012 May;50(1):93-102
1	J:249229 Espinosa-Medina I, Outin E, Picard CA, Chettouh Z, Dymecki S, Consalez GG, Coppola E, Brunet JF, Neurodevelopment. Parasympathetic ganglia derive from Schwann cell precursors. Science. 2014 Jul 4;345(6192):87-90
1	J:116626 Flynn B, Bergner AJ, Turner KN, Young HM, Anderson RB, Effect of Gdnf haploinsufficiency on rate of migration and number of enteric neural crest-derived cells. Dev Dyn. 2007 Jan;236(1):134-41
1	J:86070 Grillet N, Dubreuil V, Dufour HD, Brunet JF, Dynamic expression of RGS4 in the developing nervous system and regulation by the neural type-specific transcription factor Phox2b. J Neurosci. 2003 Nov 19;23(33):10613-21
1	J:269168 Hernandez-Miranda LR, Ibrahim DM, Ruffault PL, Larrosa M, Balueva K, Muller T, Weerd W, Stolte-Dijkstra I, Hostra RMW, Brunet JF, Fortin G, Mundlos S, Birchmeier C, Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13021-13026
1*	J:46409 Hirsch MR, Tiveron MC, Guillemot F, Brunet JF, Goridis C, Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development. 1998 Feb;125(4):599-608
1	J:138599 Hong SJ, Lardaro T, Oh MS, Huh Y, Ding Y, Kang UJ, Kirfel J, Buettner R, Kim KS, Regulation of the noradrenaline neurotransmitter phenotype by the transcription factor AP-2beta. J Biol Chem. 2008 Jun 13;283(24):16860-7
1	J:199638 Huang T, Hu J, Wang B, Nie Y, Geng J, Cheng L, Tlx3 controls cholinergic transmitter and Peptide phenotypes in a subset of prenatal sympathetic neurons. J Neurosci. 2013 Jun 26;33(26):10667-75
1	J:128441 Jacob J, Ferri AL, Milton C, Prin F, Pla P, Lin W, Gavalas A, Ang SL, Briscoe J, Transcriptional repression coordinates the temporal switch from motor to serotonergic neurogenesis. Nat Neurosci. 2007 Nov;10(11):1433-9
1	J:152424 Jacob J, Storm R, Castro DS, Milton C, Pla P, Guillemot F, Birchmeier C, Briscoe J, Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain. Development. 2009 Jul;136(14):2477-85
1	J:235102 Jarrar W, Dias JM, Ericson J, Arnold HH, Holz A, Nkx2.2 and Nkx2.9 are the key regulators to determine cell fate of branchial and visceral motor neurons in caudal hindbrain. PLoS One. 2015;10(4):e0124408
1	J:119015 Kellerer S, Schreiner S, Stolt CC, Scholz S, Bosl MR, Wegner M, Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence. Development. 2006 Aug;133(15):2875-86
1	J:323375 Lee H, Lee JJ, Park NY, Dubey SK, Kim T, Ruan K, Lim SB, Park SH, Ha S, Kovlyagina I, Kim KT, Kim S, Oh Y, Kim H, Kang SU, Song MR, Lloyd TE, Maragakis NJ, Hong YB, Eoh H, Lee G, Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS. Nat Neurosci. 2021 Dec;24(12):1673-1685
1	J:199284 Munoz-Bravo JL, Hidalgo-Figueroa M, Pascual A, Lopez-Barneo J, Leal-Cerro A, Cano DA, GDNF is required for neural colonization of the pancreas. Development. 2013 Sep;140(17):3669-79
1	J:137017 Nekrep N, Wang J, Miyatsuka T, German MS, Signals from the neural crest regulate beta-cell mass in the pancreas. Development. 2008 Jun;135(12):2151-60
1	J:295953 Niu X, Liu L, Wang T, Chuan X, Yu Q, Du M, Gu Y, Wang L, Mapping of Extrinsic Innervation of the Gastrointestinal Tract in the Mouse Embryo. J Neurosci. 2020 Aug 26;40(35):6691-6708
1*	J:110707 Pattyn A, Guillemot F, Brunet JF, Delays in neuronal differentiation in Mash1/Ascl1 mutants. Dev Biol. 2006 Jul 1;295(1):67-75
1	J:157923 Potzner MR, Tsarovina K, Binder E, Penzo-Mendez A, Lefebvre V, Rohrer H, Wegner M, Sock E, Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system. Development. 2010 Mar;137(5):775-84
1	J:76655 Qian Y, Shirasawa S, Chen CL, Cheng L, Ma Q, Proper development of relay somatic sensory neurons and D2/D4 interneurons requires homeobox genes Rnx/Tlx-3 and Tlx-1. Genes Dev. 2002 May 15;16(10):1220-33
1	J:338174 Reiprich S, Stolt CC, Schreiner S, Parlato R, Wegner M, SoxE proteins are differentially required in mouse adrenal gland development. Mol Biol Cell. 2008 Apr;19(4):1575-86
1	J:155760 Rose MF, Ren J, Ahmad KA, Chao HT, Klisch TJ, Flora A, Greer JJ, Zoghbi HY, Math1 is essential for the development of hindbrain neurons critical for perinatal breathing. Neuron. 2009 Nov 12;64(3):341-54
1	J:231113 Sajgo S, Ali S, Popescu O, Badea TC, Dynamic expression of transcription factor Brn3b during mouse cranial nerve development. J Comp Neurol. 2016 Apr 1;524(5):1033-61
1	J:124679 Schreiner S, Cossais F, Fischer K, Scholz S, Bosl MR, Holtmann B, Sendtner M, Wegner M, Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages. Development. 2007 Sep;134(18):3271-81
1	J:119655 Song MR, Shirasaki R, Cai CL, Ruiz EC, Evans SM, Lee SK, Pfaff SL, T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration. Development. 2006 Dec;133(24):4945-55
1*	J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199
1*	J:158122 Takano-Maruyama M, Chen Y, Gaufo GO, Placodal sensory ganglia coordinate the formation of the cranial visceral motor pathway. Dev Dyn. 2010 Apr;239(4):1155-61
1*	J:179737 Takano-Maruyama M, Chen Y, Gaufo GO, Differential contribution of Neurog1 and Neurog2 on the formation of cranial ganglia along the anterior-posterior axis. Dev Dyn. 2012 Feb;241(2):229-41
1	J:248588 Vassilev V, Platek A, Hiver S, Enomoto H, Takeichi M, Catenins Steer Cell Migration via Stabilization of Front-Rear Polarity. Dev Cell. 2017 Nov 20;43(4):463-479.e5
1	J:326576 Zhang M, Du S, Ou H, Cui R, Jiang N, Lin Y, Ge R, Ma D, Zhang J, Ablation of Zfhx4 results in early postnatal lethality by disrupting the respiratory center in mice. J Mol Cell Biol. 2021 Jul 6;13(3):210-224
1	J:314661 Zhang Q, Huang R, Ye Y, Guo X, Lu J, Zhu F, Gong X, Zhang Q, Yan J, Luo L, Zhuang S, Chen Y, Zhao X, Evans SM, Jiang C, Liang X, Sun Y, Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification. Cell Death Dis. 2018 Feb 14;9(2):247